China has made great achievements in the development of air separation plant, which is applied in various industries according to different needs. After decades of precipitation and development, the air separation industry is developing towards the direction of large-scale and clustering. Ultra large air separation plant can reduce the number of air separation equipment in large-scale chemical projects, thus reducing the workload of equipment investment, land use, operation and maintenance. Ultra large air separation plant can reduce a lot of cost input, but there are also strict requirements for site layout, which requires continuous accumulation of experience to ensure that the equipment can operate well in the later stage.