Operation guide for air separation unit: 1. Check all instruments, electric valves and pneumatic valves before starting the air separation unit, and close the three valves in the cooling box and the manual drain valve of the water cooling column and air cooling column; 2. Start the circulating water system and adjust the circulating water pressure; 3. Start the air compressor, precooling system and purification system; 4. Purge the fractionator.